Multiple antibiotic resistance index of some uropathogenic bacteria in outpatients- children and adolescents

Reneta Koycheva, Sevdalina Alekova

Keywords: multiple antibiotic resistance index, uropathogenic microorganisms, children and adolescents

Aim:

The treatment of urinary tract infections among children and adolescents in the outpatient medical setting is becoming an increasing challenge due to elevated prevalence of isolated bacterial strains with acquired antibiotic resistance. The goal was to be calculated the multiple antibiotic resistance index of some uropathogenic bacteria in pediatric outpatients.

Method:

A cross-sectional study was conducted among children and adolescents aged 0- 17 years with a positive urine culture in the period of time January- June 2023. It was measured the index of multiple antibiotic resistance ( MARI) of uropathogens causing infections among individuals.

Results:

21. 73% of E. coli isolates and 66.66% of Proteus mirabilis isolates had a MARI above 0.2, indicating high levels of resistance to aminopenicillins and second-generation cephalosporins. All isolates of Enterococcus faecalis had a MARI ranging from 0.467 to 0.714 and reported 100% resistance to Trimethoprim sulfamethoxazole, aminoglycosides and second- and third- generation cephalosporins.

Conclusions:

The study showed the presence of high levels of multiple antimicrobial resistance in the uropathogenic isolates of pediatric patients with significant bacteriuria in the outpatient health care. The calculation of the index of multiple antibiotic resistance sheds additional light on the severity of the existing problem.

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